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Penitrem A
60 人阅读发布时间：2021-03-29 19:11
简介 ：Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals.
Catalog_No：HY-N6776
Drug_Names：Penitrem A
Alternative_Names：
产品一级分类：天然产物
二级分类：Alkaloids
SMILES：O[C@]12[C@]34[C@@H]([C@H]([C@@H](C(C)=C)O[C@@]4([H])CC[C@@]1([C@]5(C(N6)=C7[C@](OC(C)([C@]8([H])[C@@]([C@]9([H])C8)(O)C%10=C7C6=CC(Cl)=C%10CC9=C)C)([H])[C@]5([H])CC2)C)C)O)O3
Pathway：Membrane Transporter/Ion Channel
Target：Potassium Channel
Research_Area：Neurological Disease; Cancer
国际站：Penitrem A