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简介 :Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering with the activity of DNA polymerase. Aphidicolin is an antibiotic produced by the mold Cephalosporium aphidicola. Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus. Aphidicolin potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
Catalog_No:HY-N6733
Drug_Names:Aphidicolin
Alternative_Names:
产品一级分类:天然产物
二级分类:Others
SMILES:C[C@@]12[C@]34[C@](CC[C@@]1([H])[C@@](C)([C@H](O)CC2)CO)([H])C[C@]([C@](CO)(O)CC4)([H])C3
Pathway:Cell Cycle/DNA Damage
Target:DNA/RNA Synthesis; HSV; Apoptosis; Antibiotic
Research_Area:Inflammation/Immunology; Infection
国际站:Aphidicolin
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