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Aphidicolin

102 人阅读发布时间:2021-03-29 19:06

"
简介 Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering with the activity of DNA polymerase. Aphidicolin is an antibiotic produced by the mold Cephalosporium aphidicola. Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus. Aphidicolin potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
 
Catalog_NoHY-N6733
 
Drug_NamesAphidicolin
 
Alternative_Names
 
产品一级分类天然产物
 
二级分类Others
 

SMILESC[C@@]12[C@]34[C@](CC[C@@]1([H])[C@@](C)([C@H](O)CC2)CO)([H])C[C@]([C@](CO)(O)CC4)([H])C3

PathwayCell Cycle/DNA Damage
 
TargetDNA/RNA Synthesis; HSV; Apoptosis; Antibiotic
 
Research_AreaInflammation/Immunology; Infection
 
国际站Aphidicolin
"

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