简介 :Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells.
Catalog_No:HY-13744
Alternative_Names:RFS 2000; 9-Nitrocamptothecin
产品一级分类:天然产物
二级分类:Alkaloids
SMILES:O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C([N+]([O-])=O)C=CC=C5N=C4C3=C2)=O
Pathway:Cell Cycle/DNA Damage
Target:Topoisomerase
Research_Area:Cancer
国际站:Rubitecan