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简介：Vardenafil-d5

Cat. No.：HY-B0442S

Drug_Names：Vardenafil-d5

纯度：

生物活性：Vardenafil-d5 is deuterium labeled Vardenafil. Vardenafil is a selective, orally active, potent inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil shows selectivity over PDE1 (180 nM), PDE6 (11 nM), PDE2, PDE3, and PDE4 (>1000 nM). Vardenafil competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil can be used for the research of erectile dysfunction^[1][2].

IC50 & Target：

体外研究：

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量：493.63

Formula：C₂₃H₂₇D₅N₆O₄S

CAS No.：1189685-70-8

运输条件：Room temperature in continental US; may vary elsewhere.

储存方式：

Please store the product under the recommended conditions in the Certificate of Analysis.

国际站：Vardenafil-d5

Hotline：400-820-3792

Tel：021-58955995

Email：sales@MedChemExpress.cn

Tech Support：021-58950789