简介 :GW274150 phosphate is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 μM; Kd=40 nM) and rat iNOS (ED50=1.15 μM). GW274150 phosphate displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 phosphate exerts a protective role in an acute model of lung injury inflammation.
Catalog_No:HY-12119A
Alternative_Names:
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:CC(NCCSCC[C@H](N)C(O)=O)=N.O=P(O)(O)O
Pathway:Immunology/Inflammation
Target:NO Synthase
Research_Area:Neurological Disease; Inflammation/Immunology
国际站:GW274150 phosphate