- 移动端
MedChemExpress LLC品牌商
14 年
手机商铺
商家活跃：
产品热度：
- NaN
- 0
- 0
- 2
- 2
Ophiopogonin D麦冬皂苷D,945619-74-9
￥700 - 5850
推荐产品
公司新闻/正文
Ophiopogonin D
97 人阅读发布时间：2021-03-30 15:23
简介 ：Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years.
Catalog_No：HY-N0515
Drug_Names：Ophiopogonin D
Alternative_Names：
产品一级分类：天然产物
二级分类：Saccharides and Glycosides
SMILES：C[C@@]12[C@]([C@@H]3C)([H])[C@](O[C@]34CC[C@@H](C)CO4)([H])C[C@@]1([H])[C@@](CC=C5[C@@]6([C@@H](C[C@H](O)C5)O[C@@](O[C@H](C)[C@H](O)[C@@H]7O[C@@](OC[C@@H](O)[C@@H]8O)([H])[C@@H]8O)([H])[C@@H]7O[C@@](O[C@@H](C)[C@H](O)[C@H]9O)([H])[C@@H]9O)C)([H])[C@]6([H])CC2
Pathway：Cell Cycle/DNA Damage
Target：PPAR; NF-κB; Calcium Channel
Research_Area：Inflammation/Immunology; Cardiovascular Disease
国际站：Ophiopogonin D