简介 :Actein is a triterpene glycoside isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in human bladder cancer. Actein has little toxicity in vivo.
Catalog_No:HY-N6872
Alternative_Names:
产品一级分类:天然产物
二级分类:Saccharides and Glycosides; Terpenoids and Glycosides
SMILES:C[C@]12[C@@]3([H])[C@@]4(C[C@@H](OC(C)=O)[C@@]1([C@]5([H])[C@](O[C@]6([C@H]7[C@]([C@@H](O)O6)(C)O7)C[C@H]5C)([H])C2)C)[C@@]8([C@@](C(C)([C@@H](O[C@@]9([H])[C@@H]([C@H]([C@H](O)CO9)O)O)CC8)C)([H])CC3)C4
Pathway:MAPK/ERK Pathway
Target:JNK; Akt; Apoptosis; Autophagy
Research_Area:Cancer
国际站:Actein