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Ganoderic acid D
64 人阅读发布时间：2021-03-30 09:47
简介 ：Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells. Ganoderic acid D induces HeLa human cervical carcinoma apoptosis.
Catalog_No：HY-N1511
Drug_Names：Ganoderic acid D
Alternative_Names：
产品一级分类：天然产物
二级分类：Terpenoids and Glycosides
SMILES：CC1(C)C(CC[C@]2(C)C3=C([C@@]4(C(C[C@@H]([C@]4(CC3=O)C)[C@H](C)CC(CC(C)C(O)=O)=O)=O)C)[C@@H](O)C[C@@]12[H])=O
Pathway：Cell Cycle/DNA Damage
Target：Sirtuin; Apoptosis
Research_Area：Cancer
国际站：Ganoderic acid D