简介 :Beta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermium radix, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0.7μM and 1μM for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells.
Catalog_No:HY-N4201
Alternative_Names:
产品一级分类:天然产物
二级分类:Others
SMILES:CC(C)(O)CC(O[C@@H](C(C1=O)=CC(C2=C1C(O)=CC=C2O)=O)C/C=C(C)\C)=O
Pathway:Protein Tyrosine Kinase/RTK
Target:EGFR; Src
Research_Area:Cancer
国际站:β-Hydroxyisovalerylshikonin