简介 :Radicicol is an inhibitor of Hsp90 with an IC50 value of 1 μM. Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients, leading to proteasomal degradation. Radicicol is an antifungal antibiotic with antimalarial activity, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB.
Catalog_No:HY-N6769
Alternative_Names:Monorden
产品一级分类:天然产物
二级分类:Others
SMILES:OC1=C2C(CC(/C=C/C=C\[C@@H](O3)[C@H]3C[C@@H](C)OC2=O)=O)=C(Cl)C(O)=C1
Pathway:Cell Cycle/DNA Damage
Target:HSP; Bacterial; Antibiotic
Research_Area:Infection
国际站:Radicicol