简介 :Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins. Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B.
Catalog_No:HY-N6795
Alternative_Names:
产品一级分类:天然产物
二级分类:Others
SMILES:O=C(O)/C=C(C)/C[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(C)\C=C\[C@H]1[C@@H](C)C=CC(O1)=O)=O
Pathway:Membrane Transporter/Ion Channel
Target:CRM1; HIV
Research_Area:Infection
国际站:Leptomycin A