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Equisetin
139 人阅读发布时间：2021-03-29 19:03
简介 ：Equisetin is an N-methylserine-derived acyl tetramic acid isolated from a terrestrial fungus Fusarium equiseti NRRL 5537. Equisetin is a tetramate-containing natural product with antibiotic and cytotoxic activity. Equisetin inhibits the growth of Gram-positive bacteria and HIV-1 integrase activity but shows no activity against Gram-negative bacteria. Equisetin is a Quorum-sensing inhibitor (QSI) that attenuates QS-regulated virulence phenotypes in P. aeruginosa without affecting the growth of bacterias, serves as a leading compound for the treatment of P. aeruginosa infections.
Catalog_No：HY-N6711
Drug_Names：Equisetin
Alternative_Names：
产品一级分类：天然产物
二级分类：Others
SMILES：O=C(/C1=C(O)\[C@]2(C)[C@H](/C=C/C)C=C[C@]3([H])C[C@H](C)CC[C@@]23[H])N(C)[C@@H](CO)C1=O
Pathway：Metabolic Enzyme/Protease
Target：HIV Integrase
Research_Area：Infection
国际站：Equisetin