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Calcimycin
124 人阅读发布时间：2021-03-29 18:59
简介 ：Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin induces apoptosis.
Catalog_No：HY-N6687
Drug_Names：Calcimycin
Alternative_Names：A-23187; Antibiotic A-23187
产品一级分类：天然产物
二级分类：Acids and Aldehydes
SMILES：O=C(C1=C2N=C(C[C@H]3O[C@]4(O[C@H]([C@H](C)C(C5=CC=CN5)=O)[C@H](C)C[C@H]4C)CC[C@H]3C)OC2=CC=C1NC)O
Pathway：Anti-infection
Target：Bacterial; Fungal; Apoptosis; Autophagy; Antibiotic
Research_Area：Infection; Cancer
国际站：Calcimycin