简介 :Pyrazofurin, a pyrimidine nucleoside analogue with antineoplastic activity, inhibits cell proliferation and DNA synthesis in cells by inhibiting uridine 5'-phosphate (UMP) synthase. Pyrazofurin is an active, sensitive orotate-phosphoribosyltransferase inhibitor with IC50s between 0.06-0.37 µM in the three squamous cell carcinoma (SCC) cell lines Hep-2, HNSCC-14B and HNSCC-14C.
Catalog_No:HY-122502
Alternative_Names:
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:O=C(N)C1=NNC([C@@H]2O[C@@H]([C@H]([C@H]2O)O)CO)=C1O
Pathway:Cell Cycle/DNA Damage
Target:DNA/RNA Synthesis
Research_Area:Cancer
国际站:Pyrazofurin