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SC75741
130 人阅读发布时间：2021-03-29 18:36
简介 ：SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65. SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins.
Catalog_No：HY-10496
Drug_Names：SC75741
Alternative_Names：
产品一级分类：信号通路
二级分类：生命科学试剂
SMILES：O=C(NC1=NC(C=CC(C(C2=CC=CC=C2)=O)=C3)=C3N1)C4=CSC(C(CC5)CCN5C6=NC=NC7=C6SC=C7)=N4
Pathway：NF-κB
Target：NF-κB; Influenza Virus
Research_Area：Infection; Cancer
国际站：SC75741