简介 :Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36. Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation.
Catalog_No:HY-N6712
Alternative_Names:Acetopyrrothin
产品一级分类:天然产物
二级分类:Others
SMILES:CC(NC1=C2C(N(C)C1=O)=CSS2)=O
Pathway:Anti-infection
Target:Bacterial; Antibiotic
Research_Area:Metabolic Disease; Infection
国际站:Thiolutin