简介 :MK-2 Inhibitor III (compound 16) is an orally active, selective, and ATP-competitive MAPKAP-K2 (MK-2) inhibitor with an IC50 of 0.85 nM, and is exceptional selectivity against MK-3 (IC50=0.21 μM), MK-5 (IC50=0.081 μM), ERK2 (IC50=3.44 μM), MNK1(IC50=5.7 μM) as well as CDK2, JNK2, IKK2, MSK1, and MSK2.
Catalog_No:HY-112457
Alternative_Names:
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:O=C1C2=C(NC(C3=CC(C4=CC5=CC=CC=C5N=C4)=NC=C3)=C2)CCN1.O
Pathway:MAPK/ERK Pathway
Target:MAPKAPK2 (MK2)
Research_Area:Inflammation/Immunology
国际站:MK-2 Inhibitor III