简介 :PF-4191834 (PF-04191834) is an orally active, noniron chelating, and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) (IC50=229 nM), displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX, shows no activity toward the cyclooxygenase enzymes, and is effective in inflammation and pain.
Catalog_No:HY-117048
Alternative_Names:PF-04191834
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:O=C(C1(C2=CC=CC(SC3=CC=C(C4=CC=NN4C)C=C3)=C2)CCOCC1)N
Pathway:Metabolic Enzyme/Protease
Target:Lipoxygenase
Research_Area:Inflammation/Immunology
国际站:PF-4191834