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eIF4A3-IN-1
76 人阅读发布时间：2021-03-29 16:59
简介 ：eIF4A3-IN-1 (compound 53a) is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 μM; Kd=0.043 μM), which binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 μM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD.
Catalog_No：HY-101513
Drug_Names：eIF4A3-IN-1
Alternative_Names：
产品一级分类：信号通路
二级分类：生命科学试剂
SMILES：ClC(C=C1)=CC=C1[C@@H]2N(C(C3=CC=C(Br)C=C3)=O)CCN(C(C4=C(C)N(C5=CC=CC(C#N)=C5)N=C4)=O)C2
Pathway：Cell Cycle/DNA Damage
Target：Eukaryotic Initiation Factor (eIF); Autophagy
Research_Area：Cancer
国际站：eIF4A3-IN-1