简介 :Phenoxodiol, a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner.
Catalog_No:HY-13721
Alternative_Names:Idronoxil; Dehydroequol; Haginin E
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:OC1=CC=C2C=C(C3=CC=C(O)C=C3)COC2=C1
Pathway:Apoptosis
Target:Caspase; Apoptosis; Topoisomerase
Research_Area:Cancer
国际站:Phenoxodiol