简介 :Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [3H]SP binding to the NK1 receptor with pKi values of 9.5 and 10.6 in rat and human membranes respectively, acts as a potential broad-spectrum anti-emetic agent.
Catalog_No:HY-12143
Alternative_Names:GR 205171A
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:COC1=C(CN[C@H]2CCCN[C@H]2C3=CC=CC=C3)C=C(N4N=NN=C4C(F)(F)F)C=C1.[H]Cl.[H]Cl
Pathway:GPCR/G Protein
Target:Neurokinin Receptor
Research_Area:Neurological Disease; Endocrinology; Cancer
国际站:Vofopitant dihydrochloride