简介 :20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.
Catalog_No:HY-12316
Alternative_Names:20α-Hydroxycholesterol
产品一级分类:天然产物
二级分类:Steroids
SMILES:C[C@@]1([C@@]2([H])[C@@](C)(O)CCCC(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O)C3)C)([H])[C@]4([H])CC1
Pathway:Stem Cell/Wnt
Target:Smo; Endogenous Metabolite
Research_Area:Cancer
国际站:20(S)-Hydroxycholesterol