简介 :Zaldaride maleate (CGS-9343B) is a potent, orally active and selective inhibitor of calmodulin. Zaldaride maleate (CGS-9343B) inhibits CaM (calmodulin)-stimulated cAMP phosphodiesterase activity, with an IC50 of 3.3 nM. Zaldaride maleate (CGS-9343B) prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR.
Catalog_No:HY-105118A
Alternative_Names:CGS-9343B; KW 5617
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:O=C(O)/C=C\C(O)=O.CC1(C2=CC=CN2C3=CC=CC=C3CO1)CN4CCC(N5C6=C(C=CC=C6)NC5=O)CC4
Pathway:Membrane Transporter/Ion Channel
Target:nAChR
Research_Area:Neurological Disease; Metabolic Disease; Inflammation/Immunology
国际站:Zaldaride maleate