简介 :DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC). DCPIB voltage-dependently activates potassium channels TREK1 and TRAAK and inhibits TRESK, TASK1 and TASK3 (IC50s of 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM in CPAE cells.
Catalog_No:HY-103371
Alternative_Names:
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:O=C(O)CCCOC1=CC2=C(C(C(C3CCCC3)(CCCC)C2)=O)C(Cl)=C1Cl
Pathway:Membrane Transporter/Ion Channel
Target:Chloride Channel; Potassium Channel
Research_Area:Neurological Disease
国际站:DCPIB