简介 :WAY-213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC50 of 85 nM EAAT2. It displays 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s are 5 and 3.8 μM, respectively). WAY-213613 shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function.
Catalog_No:HY-107523
Alternative_Names:
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:BrC(C=C(F)C(F)=C1)=C1OC2=CC=C(NC(C[C@H](N)C(O)=O)=O)C=C2
Pathway:Membrane Transporter/Ion Channel
Target:EAAT2
Research_Area:Neurological Disease
国际站:WAY-213613