简介 :PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes. PBIT inhibits JARID1B (KDM5B or PLU1) histone demethylase with an IC50 of about 3 μM . PBIT also inhibits JARID1A and JARID1C with IC50s of 6 μM and 4.9 μM, respectively.
Catalog_No:HY-101451
Alternative_Names:
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:O=C1N(C2=CC=C(C)C=C2)SC3=C1C=CC=C3
Pathway:Epigenetics
Target:Histone Demethylase
Research_Area:Cancer
国际站:PBIT