简介 :NU6140 is a selective CDK2-cyclin A inhibitor (IC50, 0.41 μM), exhibits 10- to 36-fold selectivity over other CDKs. NU6140 also potently inhibits Aurora A and Aurora B, with IC50s of 67 and 35 nM, respectively. Enhances the apoptotic effect, with anti-cancer activity.
Catalog_No:HY-107419
Alternative_Names:
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:CCN(CC)C(C(C=C1)=CC=C1NC2=NC(OCC3CCCCC3)=C4C(N=CN4)=N2)=O
Pathway:Cell Cycle/DNA Damage
Target:CDK; Aurora Kinase
Research_Area:Cancer
国际站:NU6140