简介 :AL 8697 is a specific and orally active p38α MAPK inhibitor with an IC50 of 6 nM. AL 8697 displays 14-fold greater inhibition of p38α compared to p38β (IC50=82 nM), and 300-fold selectivity for p38α over a panel of 91 kinases. Anti-inflammatory activity.
Catalog_No:HY-108645
Alternative_Names:
产品一级分类:信号通路
二级分类:生命科学试剂
SMILES:O=C(NC1CC1)C2=CC(F)=C(C)C(C3=C(F)C4=NN=C(C(C)(C)C)N4C=C3F)=C2
Pathway:MAPK/ERK Pathway
Target:p38 MAPK; Autophagy
Research_Area:Inflammation/Immunology
国际站:AL 8697